by Ervin Laszlo (Author), Pier Mario Biava (Author), Deepak Chopra (Foreword)

A look at the future of medicine based on cutting-edge stem cell research.

  • Shares Dr. Biava’s groundbreaking research on stem cell differentiation stage factors (SCDSFs) as a cellular “reprogramming” treatment for cancer and other degenerative diseases;
  • Explains how SCDSFs restore communication between cells and the epigenetic code, the information that programs the normal function and growth of every living cell;
  • Explores how the universe operates like a cosmic information-network and how this new scientific worldview will shape the future of healing and medicine.

The universe is not a mechanical system of matter–it operates like a cosmic network that runs on and is connected by information. Information “in-forms” and underlies all of the physical world, including the human body. In this book, Pier Mario Biava, M.D., and Ervin Laszlo, Ph.D., show how this “information” worldview can be applied to healing and medicine and, specifically, how it underlies a revolutionary new approach to cancer and disease treatment, one that works directly with the epigenetic code–the information that programs the function and growth of every living cell.

The authors explain how tumor growth and cellular dysfunction are manifestations of disconnections in the information network of an organism. Unveiling Dr. Biava’s groundbreaking research on stem cell differentiation stage factors (SCDSFs), they explain how SCDSFs work directly as epigenetic regulators to reconnect aberrant cells to the body’s information network and reset them to their original function–in the case of cancer cells transforming them from malignant to benign, from dysfunction back to normalcy and health. Dr. Biava’s research on SCDSFs–derived from Zebrafish embryos, which have a very high percentage of proteins identical with those of human beings–has shown good success in reprogramming and inhibiting cancer cells in clinical trials with patients with advanced liver cancer, as well as success in in vitro studies with 7 different human tumor lines. SCDSFs have also shown promise in the treatment of chronic diseases such as psoriasis and neurodegenerative diseases. This research will also allow the development of new treatments for Alzheimer’s, Parkinson’s, and multiple sclerosis.

Unveiling the holistic future of medicine, the authors show how we will no longer need to approach the treatment of cancer and other degenerative diseases as a “fight,” but as a restoration of our cells’ original programming. With the advent of Information Medicine, we now have the power to program ourselves to heal.

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Table of Contents


Deepak Chopra, M.D.

It’s a natural part of any discovery to find yourself lying at night, settling down from the excitement of a breakthrough, and saying to yourself, “If I’m right, this changes everything.” Most of the time, however, everything doesn’t change. If the discovery winds up being accepted, you might be fortunate, and a few things will change.


  • The New Paradigm in Physics
  • The New Paradigm of Evolution
  • Information Medicine: The New Paradigm in Health and Healing


  • Reprogramming Cancer Stem-like Cells       
  • Review of the Experimental Evidence
  • Conclusions Based on the Experiments
  • Addendum: Declaration of a Committee of Oncologists


  • Seven Assessments
    • Raoul Goldberg
    • Maria Sagi
    • Dwight McKee
    • Larry Dossey
    • Giulio Sapelli
    • Kingsley Dennis
    • Alessandro Pizzoccaro


  • Introduction
  • Editorials
    • Complex Therapeutical Approaches to Complex Diseases
    • Reprogramming of Normal and Cancer Stem Cells

  • The Principal Reports
    • Cancer and Cell-DifferenTiation: A Model to Explain Malignancy

    • Stem Cell Differentiation Stage Factors from Zebrafish Embryo:
      A Novel Strategy to Modulate the Fate of Normal and Pathological Human (Stem) Cells
    • Getting an Insight into the Complexity of Major Chronic Inflammatory and Degenerative Diseases:
      A Possible New Systemic Approach to Their Treatment
    • Cancer: A Problem of Developmental Biology;
      Evidence for Reprogramming and Differentiation Therapy

  • Abstracts of Selected Studies
    • Stem Cell Differentiation Stage Factors Stage and Their Role in Triggering Symmetry Breaking Processes During Cancer Development

    • The Role of Neuroendocrine Cells in Prostate Cancer

    • A Systemic Approach to Cancer Treatment:
      Reprogramming Focused on Endocrine-Related Cancers

    • The Zebrafish Embryo Derivative Affects Cell Viability of Epidermal Cells:
      A Possible Role in the Treatment of Psoriasis

    • Cancer Cell Reprogramming:
      Stem Cell Differentiation Stage Factors and an Agent-Based Model to Optimize Cancer Treatment

    • Zebrafish Stem Cell Differentiation Stage Factors Suppress Bcl-XI Release and Enhance 5-Fu-Mediated Apoptosis in Colon Cancer Cells

    • Embryonic Morphogenetic Fields Induce Phenotypic Reversion in Cancer Cells

    • Cancer, Cell Death and Differentiation:
      The Role of Epigenetic Code in Tumor Growth Control

    • Zebrafish Embryo Proteins Induce Apoptosis in Human Colon Cancer Cells (Caco2)

    • Treatment with Stem Cell Differentiation Stage Factors of Intermediate-Advanced Hepatocellular Carcinoma
  • Laszlo’s Books on the New Paradigm
  • Biava’s Books on the New Discovery

About the Co-Authors

Ervin Laszlo is a philosopher and systems scientist. Twice nominated for the Nobel Peace Prize, he has published more than 75 books and over 400 articles and research papers. The subject of the one-hour PBS special Life of a Modern-Day Genius, Laszlo is the founder and president of the international think tank the Club of Budapest and of the prestigious Laszlo Institute of New Paradigm Research. The winner of the 2017 Luxembourg Peace Prize, he lives in Tuscany. In 2019, Ervin Laszlo was cited as one of the “100 Most Spiritually Influential Living People in the World” according to Watkins Mind Body Spirit magazine.

Pier Mario Biava, M.D., has been studying the relationship between cancer and cell differentiation for more than 3 decades. The author of over 100 scientific publications and 6 books, he works at the Institute of Research and Treatment in Milan.


Get Information Medicine: The Revolutionary Cell-Reprogramming Discovery that Reverses Cancer and Degenerative Diseases

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The Laszlo Institute of New Paradigm Research